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TargetAlpha carbonic anhydrase
LigandBDBM10872
Substrate/Competitorn/a
Meas. Tech.ChEMBL_700658
Ki 19.7±n/a nM
Citation Bertucci, AInnocenti, AScozzafava, ATambutté, SZoccola, DSupuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett21:710-4 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha carbonic anhydrase
Name:Alpha carbonic anhydrase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:36650.57
Organism:Stylophora pistillata
Description:ChEMBL_700658
Residue:323
Sequence:
MKLSLFISSLLAMIVACPNLAESAGSWTYRDPEGPDTWKHHYKDCEGHEQSPINIVPKDT
FFEPGLADLVVNYEKSVSAKLFNNGHTVQATFLTGKSNISGGNLTSHFRALQMHFHWGSE
NSRGSEHQVGGRKFPLEIHIVHYNAEKYPSVSEAVDKGDGLAVLGILVELQVQDNPVFDV
MVDNLDKARYKGNEVILPSLQPFSFLPHDIAQYYTYRGSLTTPGCFESVQWFVFNHTFPI
SQAQLDKFRDLFDSEKQDTKKLPLVDNYRPVQPLYGRSVSEASNALLFPVARHQTKLWIA
WDSLMTRQYFMKQQSICALYQPQ
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM10872
NameBDBM10872
Synonyms:4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide | CHEMBL7146 | aromatic/heteroaromatic sulfonamide 17
TypeSmall organic molecule
Emp. Form.C14H17N3O4S2
Mol. Mass.355.432
SMILESNc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a