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Target
Carbonic anhydrase
Ligand
BDBM50334355
Substrate
n/a
Meas. Tech.
ChEMBL_700108 (CHEMBL1646990)
Ki
87±n/a nM
Citation
 Pacchiano, F; Carta, F; Vullo, D; Scozzafava, A; Supuran, CT Inhibition ofß-carbonic anhydrases with ureido-substituted benzenesulfonamides. Bioorg Med Chem Lett 21:102-5 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE)
Type:
PROTEIN
Mol. Mass.:
80567.22
Organism:
Mycobacterium tuberculosis
Description:
ChEMBL_878775
Residue:
764
Sequence:
MTIPRSQHMSTAVNSCTEAPASRSQWMLANLRHDVPASLVVFLVALPLSLGIAIASGAPIIAGVIAAVVGGIVAGAVGGSPVQVSGPAAGLTVVVAELIDELGWPMLCLMTIAAGALQIVFGLSRMARAALAIAPVVVHAMLAGIGITIALQQIHVLLGGTSHSSAWRNIVALPDGILHHELHEVIVGGTVIAILLMWSKLPAKVRIIPGPLVAIAGATVLALLPVLQTERIDLQGNFFDAIGLPKLAEMSPGGQPWSHEISAIALGVLTIALIASVESLLSAVGVDKLHHGPRTDFNREMVGQGSANVVSGLLGGLPITGVIVRSSANVAAGARTRMSTILHGVWILLFASLFTNLVELIPKAALAGLLIVIGAQLVKLAHIKLAWRTGNFVIYAITIVCVVFLNLLEGVAIGLVVAIVFLLVRVVRAPVEVKPVGGEQSKRWRVDIDGTLSFLLLPRLTTVLSKLPEGSEVTLNLNADYIDDSVSEAISDWRRAHETRGGVVAIVETSPAKLHHAHARPPKRHFASDPIGLVPWRSARGKDRGSASVLDRIDEYHRNGAAVLHPHIAGLTDSQDPYELFLTCADSRILPNVITASGPGDLYTVRNLGNLVPTDPDDRSVDAALDFAVNQLGVSSVVVCGHSSCAAMTALLEDDPANTTTPMMRWLENAHDSLVVFRNHHPARRSAESAGYPEADQLSIVNVAVQVERLTRHPILATAVAAADLQVIGIFFDISTARVYEVGPNGIICPDEPADRPVDHESAQ
  
Inhibitor
Name:
BDBM50334355
Synonyms:
4-(3-(4-bromophenyl)ureido)benzenesulfonamide | 4-({[(4'-Bromophenyl)amino]carbonyl}amino)benzenesulfonamide | CHEMBL1643291
Type:
Small organic molecule
Emp. Form.:
C13H12BrN3O3S
Mol. Mass.:
370.222
SMILES:
NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Br)cc2)cc1
Structure:
Search PDB for entries with ligand similarity: