| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor protein alpha-7 subunit |
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| Ligand | BDBM50336020 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_717230 |
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| Ki | 57±n/a nM |
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| Citation |  Lin, SW; Sun, Q; Ge, ZM; Wang, X; Ye, J; Li, RT Synthesis and structure-analgesic activity relationships of a novel series of monospirocyclopiperazinium salts (MSPZ). Bioorg Med Chem Lett21:940-3 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor protein alpha-7 subunit |
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| Name: | Neuronal acetylcholine receptor protein alpha-7 subunit |
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| Synonyms: | CHRNA7 | Cholinergic, Nicotinic Alpha7 | NACHRA7 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR-alpha 7) | Nicotinic acetylcholine receptor alpha-7 (alpha7 nAChR) |
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| Type: | n/a |
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| Mol. Mass.: | 56448.33 |
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| Organism: | Homo sapiens (Human) |
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| Description: | CHRNA7 (NACHRA7) |
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| Residue: | 502 |
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| Sequence: | MRCSPGGVWLALAASLLHVSLQGEFQRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLL
QIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADE
RFDATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDL
QMQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIP
CVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFAST
MIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVILLNWCAWFLRMKRPGEDKVRPACQHK
QRRCSLASVEMSAVAPPPASNGNLLYIGFRGLDGVHCVPTPDSGVVCGRMACSPTHDEHL
LHGGQPPEGDPDLAKILEEVRYIANRFRCQDESEAVCSEWKFAACVVDRLCLMAFSVFTI
ICTIGILMSAPNFVEAVSKDFA
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| BDBM50336020 |
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| Name | BDBM50336020 |
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| Synonyms: | CHEMBL1669092 | N,N,N-trimethyl-1-(4-styrylphenoxy)propan-2-aminium iodide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H26NO |
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| Mol. Mass. | 296.426 |
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| SMILES | CC(COc1ccc(\C=C/c2ccccc2)cc1)[N+](C)(C)C |
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| Structure | 
|
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| n/a |
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