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Target
Pancreatic triacylglycerol lipase
Ligand
BDBM50337363
Substrate
n/a
Meas. Tech.
ChEMBL_726519 (CHEMBL1685414)
IC50
9100±n/a nM
Citation
 Kim, TH; Kim, JK; Ito, H; Jo, C Enhancement of pancreatic lipase inhibitory activity of curcumin by radiolytic transformation. Bioorg Med Chem Lett 21:1512-4 (2011) [PubMed]  Article 
Target
Name:
Pancreatic triacylglycerol lipase
Synonyms:
LIPP_PIG | PL | PNLIP | PTL | Pancreatic lipase | Pancreatic triacylglycerol lipase
Type:
Enzyme
Mol. Mass.:
50080.69
Organism:
Sus scrofa (Pig)
Description:
P00591
Residue:
450
Sequence:
SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNYQELVADPSTITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESVNCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEVLKSSLGYSPSNVHVIGHSLGSHAAGEAGRRTNGTIERITGLDPAEPCFQGTPELVRLDPSDAKFVDVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQKNILSQIVDIDGIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPCPSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGKKVTGHILVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVKFIWYNNNVINPTLPRVGASKITVERNDGKVYDFCSQETVREEVLLTLNPC
  
Inhibitor
Name:
BDBM50337363
Synonyms:
CHEMBL1682392 | threo-1-(3-methoxy-4-hydroxy-phenyl)-propan-1,2-diol
Type:
Small organic molecule
Emp. Form.:
C10H14O4
Mol. Mass.:
198.2158
SMILES:
COc1cc(ccc1O)[C@H](O)[C@H](C)O |r|
Structure:
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