Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50338152
Substrate
n/a
Meas. Tech.
ChEMBL_727755 (CHEMBL1686114)
IC50
>50000±n/a nM
Citation
 Bonafoux, D; Abibi, A; Bettencourt, B; Burchat, A; Ericsson, A; Harris, CM; Kebede, T; Morytko, M; McPherson, M; Wallace, G; Wu, X Thienopyrrole acetic acids as antagonists of the CRTH2 receptor. Bioorg Med Chem Lett 21:1861-4 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50338152
Synonyms:
2-(5-methyl-6-(4-(methylsulfonyl)phenylsulfonyl)-6H-thieno[2,3-b]pyrrol-4-yl)acetic acid | CHEMBL1684721
Type:
Small organic molecule
Emp. Form.:
C16H15NO6S3
Mol. Mass.:
413.488
SMILES:
Cc1c(CC(O)=O)c2ccsc2n1S(=O)(=O)c1ccc(cc1)S(C)(=O)=O
Structure:
Search PDB for entries with ligand similarity: