Reaction Details Report a problem with these data
Target
Oxoeicosanoid receptor 1
Ligand
BDBM50338299
Substrate
n/a
Meas. Tech.
ChEMBL_728026 (CHEMBL1686897)
EC50
56±n/a nM
Citation
 Patel, P; Anumolu, JR; Powell, WS; Rokach, J 5-oxo-15-HETE: total synthesis and bioactivity. Bioorg Med Chem Lett 21:1857-60 (2011) [PubMed]  Article 
Target
Name:
Oxoeicosanoid receptor 1
Synonyms:
5-oxo-ETE G-protein coupled receptor | G-protein coupled receptor 170 | G-protein coupled receptor R527 | G-protein coupled receptor TG1019 | GPR170 | OXER1 | OXER1_HUMAN | Oxoeicosanoid receptor 1 | TG 1019 | TG1019
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45833.20
Organism:
Homo sapiens (Human)
Description:
TG 1019 0 HUMAN::Q8TDS5
Residue:
423
Sequence:
MLCHRGGQLIVPIIPLCPEHSCRGRRLQNLLSGPWPKQPMELHNLSSPSPSLSSSVLPPSFSPSPSSAPSAFTTVGGSSGGPCHPTSSSLVSAFLAPILALEFVLGLVGNSLALFIFCIHTRPWTSNTVFLVSLVAADFLLISNLPLRVDYYLLHETWRFGAAACKVNLFMLSTNRTASVVFLTAIALNRYLKVVQPHHVLSRASVGAAARVAGGLWVGILLLNGHLLLSTFSGPSCLSYRVGTKPSASLRWHQALYLLEFFLPLALILFAIVSIGLTIRNRGLGGQAGPQRAMRVLAMVVAVYTICFLPSIIFGMASMVAFWLSACRSLDLCTQLFHGSLAFTYLNSVLDPVLYCFSSPNFLHQSRALLGLTRGRQGPVSDESSYQPSRQWRYREASRKAEAIGKLKVQGEVSLEKEGSSQG
  
Inhibitor
Name:
BDBM50338299
Synonyms:
15-hydroxy-5-oxo-eicosa-6(E),8(Z),11(Z),13(E)tetraenoic acid | CHEMBL1682258
Type:
Small organic molecule
Emp. Form.:
C20H30O4
Mol. Mass.:
334.4498
SMILES:
CCCCC[C@H](O)\C=C\C=C/CC=CC=CC(=O)CCCC(O)=O |r,w:12.11,14.13|
Structure:
Search PDB for entries with ligand similarity: