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Target
Alpha-glucosidase MAL62
Ligand
BDBM50341204
Substrate
n/a
Meas. Tech.
ChEMBL_742391 (CHEMBL1768949)
IC50
2350000±n/a nM
Citation
 Brindis, F; Rodríguez, R; Bye, R; González-Andrade, M; Mata, R (Z)-3-butylidenephthalide from Ligusticum porteri , ana-glucosidase inhibitor. J Nat Prod 74:314-20 (2011) [PubMed]  Article 
Target
Name:
Alpha-glucosidase MAL62
Synonyms:
MAL62 | MAL62_YEASX | MAL6S
Type:
PROTEIN
Mol. Mass.:
68174.43
Organism:
Saccharomyces cerevisiae
Description:
ChEMBL_942538
Residue:
584
Sequence:
MTISDHPETEPKWWKEATIYQIYPASFKDSNNDGWGDLKGITSKLQYIKDLGVDAIWVCPFYDSPQQDMGYDISNYEKVWPTYGTNEDCFELIDKTHKLGMKFITDLVINHCSTEHEWFKESRSSKTNPKRDWFFWRPPKGYDAEGKPIPPNNWKSFFGGSAWTFDETTNEFYLRLFASRQVDLNWENEDCRRAIFESAVGFWLDHGVDGFRIDTAGLYSKRPGLPDSPIFDKTSKLQHPNWGSHNGPRIHEYHQELHRFMKNRVKDGREIMRVGEVAHGSDNALYTSAARYEVSEVFSFTHVEVGTSPFFRYNIVPFTLKQWKEAIASNFLFINGTDSWATTYIENHDQARSITRFADDSPKYRKISGKLLTLLECSLTGTLYVYQGQEIGQINFKEWPIEKYEDVDVKNNYEIIKKSFGKNSKEMKDFFKGIALLSRDHSRTPMPWTKDKPNAGFTGPDVKPWFFLNESFEQGINVEQESRDDDSVLNFWKRALQARKKYKELMIYGYDFQFIDLDSDQIFSFTKEYEDKTLFAALNFSGEEIEFSLPREGASLSFILGNYDDTDVSSRVLKPWEGRIYLVK
  
Inhibitor
Name:
BDBM50341204
Synonyms:
(Z)-3-butylidenephthalide | CHEMBL1765390
Type:
Small organic molecule
Emp. Form.:
C12H12O2
Mol. Mass.:
188.2225
SMILES:
CCC\C=C1\OC(=O)c2ccccc12
Structure:
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