Reaction Details Report a problem with these data
Target
Ribose-5-phosphate isomerase B
Ligand
BDBM50148767
Substrate
n/a
Meas. Tech.
ChEMBL_744989 (CHEMBL1772004)
Ki
400000±n/a nM
Citation
 Yep, A; Sorenson, RJ; Wilson, MR; Showalter, HD; Larsen, SD; Keller, PR; Woodard, RW Enediol mimics as inhibitors of the D-arabinose 5-phosphate isomerase (KdsD) from Francisella tularensis. Bioorg Med Chem Lett 21:2679-82 (2011) [PubMed]  Article 
Target
Name:
Ribose-5-phosphate isomerase B
Synonyms:
Phosphoriboisomerase B | RPIB_MYCTU | rpiB
Type:
PROTEIN
Mol. Mass.:
17277.83
Organism:
Mycobacterium tuberculosis
Description:
ChEMBL_744989
Residue:
162
Sequence:
MSGMRVYLGADHAGYELKQRIIEHLKQTGHEPIDCGALRYDADDDYPAFCIAAATRTVADPGSLGIVLGGSGNGEQIAANKVPGARCALAWSVQTAALAREHNNAQLIGIGGRMHTVAEALAIVDAFVTTPWSKAQRHQRRIDILAEYERTHEAPPVPGAPA
  
Inhibitor
Name:
BDBM50148767
Synonyms:
2,3-dihydroxy-4-(hydroxyamino)-4-oxobutyl dihydrogen phosphate | 4-PHOSPHO-D-ERYTHRONOHYDROXAMIC ACID | CHEMBL116018 | Phosphoric acid mono-((1R,3R)-2,3-dihydroxy-3-hydroxycarbamoyl-propyl) ester
Type:
Small organic molecule
Emp. Form.:
C4H10NO8P
Mol. Mass.:
231.0979
SMILES:
ONC(=O)[C@H](O)[C@H](O)COP(O)(O)=O
Structure:
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