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Target
Fe(3+)-Zn(2+) purple acid phosphatase
Ligand
BDBM50343030
Substrate
n/a
Meas. Tech.
ChEMBL_744350 (CHEMBL1772256)
pH
4.9±n/a
Ki
5000±n/a nM
Comments
extracted
Citation
 Mohd-Pahmi, SH; Hussein, WM; Schenk, G; McGeary, RP Synthesis, modelling and kinetic assays of potent inhibitors of purple acid phosphatase. Bioorg Med Chem Lett 21:3092-4 (2011) [PubMed]  Article 
Target
Name:
Fe(3+)-Zn(2+) purple acid phosphatase
Synonyms:
Iron(III)-zinc(II) purple acid phosphatase | PAP | PPAF_PHAVU
Type:
PROTEIN
Mol. Mass.:
52875.57
Organism:
Phaseolus vulgaris
Description:
ChEMBL_560427
Residue:
459
Sequence:
MGVVKGLLALALVLNVVVVSNGGKSSNFVRKTNKNRDMPLDSDVFRVPPGYNAPQQVHITQGDLVGRAMIISWVTMDEPGSSAVRYWSEKNGRKRIAKGKMSTYRFFNYSSGFIHHTTIRKLKYNTKYYYEVGLRNTTRRFSFITPPQTGLDVPYTFGLIGDLGQSFDSNTTLSHYELSPKKGQTVLFVGDLSYADRYPNHDNVRWDTWGRFTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKRASAHIIVLSSYSAYGRGTPQYTWLKKELRKVKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFEAWFVKYKVDVVFAGHVHAYERSERVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPEYSAFREASFGHGMFDIKNRTHAHFSWNRNQDGVAVEADSVWFFNRHWYPVDDST
  
Inhibitor
Name:
BDBM50343030
Synonyms:
CHEMBL1771210 | rac-(Dodecanamido(naphthalen-1-yl)methyl)phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C23H34NO4P
Mol. Mass.:
419.4941
SMILES:
CCCCCCCCCCCC(=O)NC(c1cccc2ccccc12)P(O)(O)=O
Structure:
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