| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor |
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| Ligand | BDBM50343609 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_746050 |
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| Ki | 0.022±n/a nM |
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| Citation |  Koike, T; Hoashi, Y; Takai, T; Nakayama, M; Yukuhiro, N; Ishikawa, T; Hirai, K; Uchikawa, O 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT2-selective agonists. J Med Chem54:3436-44 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor |
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| Name: | Melatonin receptor |
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| Synonyms: | MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 40203.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49286 |
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| Residue: | 362 |
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| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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| BDBM50343609 |
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| Name | BDBM50343609 |
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| Synonyms: | CHEMBL1774512 | N-[2-(1,6-Dihydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C15H17NO2 |
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| Mol. Mass. | 243.301 |
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| SMILES | CC(=O)NCCC1=CCc2ccc3OCCc3c12 |t:6| |
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| Structure | 
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| n/a |
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