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Reaction Details
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TargetMelatonin receptor
LigandBDBM50343609
Substrate/Competitorn/a
Meas. Tech.ChEMBL_746050
Ki 0.022±n/a nM
Citation Koike, THoashi, YTakai, TNakayama, MYukuhiro, NIshikawa, THirai, KUchikawa, O 1,6-Dihydro-2H-indeno[5,4-b]furan derivatives: design, synthesis, and pharmacological characterization of a novel class of highly potent MT2-selective agonists. J Med Chem54:3436-44 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1B | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:Enzyme
Mol. Mass.:40203.54
Organism:Homo sapiens (Human)
Description:P49286
Residue:362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
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BDBM50343609
NameBDBM50343609
Synonyms:CHEMBL1774512 | N-[2-(1,6-Dihydro-2H-indeno[5,4-b]furan-8-yl)ethyl]acetamide
TypeSmall organic molecule
Emp. Form.C15H17NO2
Mol. Mass.243.301
SMILESCC(=O)NCCC1=CCc2ccc3OCCc3c12 |t:6|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a