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Target
Sialidase-4
Ligand
BDBM50343690
Substrate
n/a
Meas. Tech.
ChEMBL_745979 (CHEMBL1775278)
IC50
>1000000±n/a nM
Citation
 Albohy, A; Mohan, S; Zheng, RB; Pinto, BM; Cairo, CW Inhibitor selectivity of a new class of oseltamivir analogs against viral neuraminidase over human neuraminidase enzymes. Bioorg Med Chem 19:2817-22 (2011) [PubMed]  Article 
Target
Name:
Sialidase-4
Synonyms:
NEU4 | NEUR4_HUMAN | Sialidase 4
Type:
PROTEIN
Mol. Mass.:
51579.82
Organism:
Homo sapiens (Human)
Description:
ChEMBL_960637
Residue:
484
Sequence:
MGVPRTPSRTVLFERERTGLTYRVPSLLPVPPGPTLLAFVEQRLSPDDSHAHRLVLRRGTLAGGSVRWGALHVLGTAALAEHRSMNPCPVHDAGTGTVFLFFIAVLGHTPEAVQIATGRNAARLCCVASRDAGLSWGSARDLTEEAIGGAVQDWATFAVGPGHGVQLPSGRLLVPAYTYRVDRRECFGKICRTSPHSFAFYSDDHGRTWRCGGLVPNLRSGECQLAAVDGGQAGSFLYCNARSPLGSRVQALSTDEGTSFLPAERVASLPETAWGCQGSIVGFPAPAPNRPRDDSWSVGPGSPLQPPLLGPGVHEPPEEAAVDPRGGQVPGGPFSRLQPRGDGPRQPGPRPGVSGDVGSWTLALPMPFAAPPQSPTWLLYSHPVGRRARLHMGIRLSQSPLDPRSWTEPWVIYEGPSGYSDLASIGPAPEGGLVFACLYESGARTSYDEISFCTFSLREVLENVPASPKPPNLGDKPRGCCWPS
  
Inhibitor
Name:
BDBM50343690
Synonyms:
(4R,5R)-4-acetamido-3-(4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl)-5-(pentan-3-yloxy)cyclohex-2-enecarboxylic acid | CHEMBL1773349
Type:
Small organic molecule
Emp. Form.:
C19H30N4O5
Mol. Mass.:
394.4653
SMILES:
CCC(CC)O[C@@H]1CC(C=C([C@H]1NC(C)=O)n1cc(nn1)C(C)(C)O)C(O)=O |r,c:9|
Structure:
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