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Target
Egl nine homolog 1
Ligand
BDBM50348089
Substrate
n/a
Meas. Tech.
ChEMBL_757459 (CHEMBL1804279)
IC50
69700±n/a nM
Citation
 Kwon, HS; Choi, YK; Kim, JW; Park, YK; Yang, EG; Ahn, DR Inhibition of a prolyl hydroxylase domain (PHD) by substrate analog peptides. Bioorg Med Chem Lett 21:4325-8 (2011) [PubMed]  Article 
Target
Name:
Egl nine homolog 1
Synonyms:
C1orf12 | EGLN1 | EGLN1_HUMAN | Egl nine homolog 1 (EGLN1) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2) | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) | Prolyl hydroxylase domain-containing protein 2 (PHD2)
Type:
Protein
Mol. Mass.:
46035.59
Organism:
Homo sapiens (Human)
Description:
Q9GZT9
Residue:
426
Sequence:
MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPSDSVGKDVF
  
Inhibitor
Name:
BDBM50348089
Synonyms:
CHEMBL1800368
Type:
Small organic molecule
Emp. Form.:
C5H7NO2S
Mol. Mass.:
145.18
SMILES:
OC(=O)[C@@H]1CC(=S)CN1 |r|
Structure:
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