Reaction Details Report a problem with these data
Target
3-oxoacyl-[acyl-carrier-protein] synthase 3
Ligand
BDBM50349319
Substrate
n/a
Meas. Tech.
ChEMBL_760083 (CHEMBL1810406)
Ki
0.000609790±n/a nM
Citation
 Zhang, HJ; Zhu, DD; Li, ZL; Sun, J; Zhu, HL Synthesis, molecular modeling and biological evaluation ofß-ketoacyl-acyl carrier protein synthase III (FabH) as novel antibacterial agents. Bioorg Med Chem 19:4513-9 (2011) [PubMed]  Article 
Target
Name:
3-oxoacyl-[acyl-carrier-protein] synthase 3
Synonyms:
3-oxoacyl-[acyl-carrier-protein] synthase | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | 3-oxoacyl-[acyl-carrier-protein] synthase III | Beta-ketoacyl-ACP synthase III (FabH)
Type:
Enzyme
Mol. Mass.:
33506.68
Organism:
Escherichia coli
Description:
C3TDZ2
Residue:
317
Sequence:
MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVTELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF
  
Inhibitor
Name:
BDBM50349319
Synonyms:
CHEMBL1807656
Type:
Small organic molecule
Emp. Form.:
C17H19N3O5
Mol. Mass.:
345.3499
SMILES:
COc1ccc(\C=C\C(=O)OC(C)Cn2c(C)ncc2[N+]([O-])=O)cc1
Structure:
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