Target
Arginase
Ligand
BDBM50350309
Substrate
n/a
Meas. Tech.
ChEMBL_762138 (CHEMBL1816209)
Ki
260000±n/a nM
Citation
 Ilies, MDi Costanzo, LDowling, DPThorn, KJChristianson, DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem 54:5432-43 (2011) [PubMed]  Article 
Target
Name:
Arginase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
46502.96
Organism:
Plasmodium falciparum
Description:
ChEMBL_762136
Residue:
411
Sequence:
MLDTIESYIKSHKEKENLYVKKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGDNEMKQEKKTNNYINNNDNNNDNNNDNNNDNNNNCYIPNGVIKEKKHDLSNNKMNGYVNHNFYGNYEENNVISTNDKYKNNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFEWSEKLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV
  
Inhibitor
Name:
BDBM50350309
Synonyms:
CHEMBL1812662
Type:
Small organic molecule
Emp. Form.:
C7H16BNO4
Mol. Mass.:
189.017
SMILES:
CC([NH3+])(CCCCB(O)O)C([O-])=O
Structure:
Search PDB for entries with ligand similarity: