Reaction Details Report a problem with these data
Target
Prostaglandin F2-alpha receptor
Ligand
BDBM50350350
Substrate
n/a
Meas. Tech.
ChEMBL_761108 (CHEMBL1815362)
Ki
2600±n/a nM
Citation
 Iwahashi, M; Shimabukuro, A; Onoda, T; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Discovery of selective indole-based prostaglandin D2 receptor antagonist. Bioorg Med Chem 19:4574-88 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_MOUSE | ProstaglandinF2Alpha | Ptgfr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40714.02
Organism:
MOUSE
Description:
ProstaglandinF2Alpha PTGFR MOUSE::P43117
Residue:
366
Sequence:
MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL
  
Inhibitor
Name:
BDBM50350350
Synonyms:
CHEMBL1813120
Type:
Small organic molecule
Emp. Form.:
C29H28N2O5
Mol. Mass.:
484.543
SMILES:
CN1C[C@@H](COc2ccc(C(=O)n3c(C)c(CC(O)=O)c4ccccc34)c(C)c2)Oc2ccccc12 |r|
Structure:
Search PDB for entries with ligand similarity: