Reaction Details Report a problem with these data
Target
Prostaglandin F2-alpha receptor
Ligand
BDBM50351483
Substrate
n/a
Meas. Tech.
ChEMBL_764677 (CHEMBL1821229)
Ki
>10000±n/a nM
Citation
 Iwahashi, M; Takahashi, E; Tanaka, M; Matsunaga, Y; Okada, Y; Matsumoto, R; Nambu, F; Nakai, H; Toda, M Design and synthesis of new prostaglandin D2 receptor antagonists. Bioorg Med Chem 19:5361-71 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_MOUSE | ProstaglandinF2Alpha | Ptgfr
Type:
Enzyme Catalytic Domain
Mol. Mass.:
40714.02
Organism:
MOUSE
Description:
ProstaglandinF2Alpha PTGFR MOUSE::P43117
Residue:
366
Sequence:
MSMNSSKQPVSPAAGLIANTTCQTENRLSVFFSIIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGGIAVFVYASDKDWIRFDQSNILCSIFGISMVFSGLCPLFLGSAMAIERCIGVTNPIFHSTKITSKHVKMILSGVCMFAVFVAVLPILGHRDYQIQASRTWCFYNTEHIEDWEDRFYLLFFSFLGLLALGVSFSCNAVTGVTLLRVKFRSQQHRQGRSHHLEMIIQLLAIMCVSCVCWSPFLVTMANIAINGNNSPVTCETTLFALRMATWNQILDPWVYILLRKAVLRNLYKLASRCCGVNIISLHIWELSSIKNSLKVAAISESPAAEKESQQASSEAGL
  
Inhibitor
Name:
BDBM50351483
Synonyms:
CHEMBL1819622
Type:
Small organic molecule
Emp. Form.:
C25H22Cl2N2O5
Mol. Mass.:
501.359
SMILES:
CN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3Cl)c(Cl)c2)Oc2ccccc12 |r|
Structure:
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