Reaction Details Report a problem with these data
Target
CviR transcriptional regulator
Ligand
BDBM50351516
Substrate
n/a
Meas. Tech.
ChEMBL_765227 (CHEMBL1827780)
IC50
377±n/a nM
Citation
 Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article 
Target
Name:
CviR transcriptional regulator
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
29723.76
Organism:
Chromobacterium violaceum
Description:
ChEMBL_765227
Residue:
265
Sequence:
MVISKPINARPLPAGLTASQQWTLLEWIHMAGHIETENELKAFLDQVLSQAPSERLLLALGRLNNQNQIQRLERVLNVSYPSDWLDQYMKENYAQHDPILRIHLGQGPVMWEERFNRAKGAEEKRFIAEATQNGMGSGITFSAASERNNIGSILSIAGREPGRNAALVAMLNCLTPHLHQAAIRVANLPPASPSNMPLSQREYDIFHWMSRGKTNWEIATILDISERTVKFHVANVIRKLNANNRTHAIVLGMHLAMPPSTVANE
  
Inhibitor
Name:
BDBM50351516
Synonyms:
CHEMBL1823953
Type:
Small organic molecule
Emp. Form.:
C14H16ClNO4
Mol. Mass.:
297.734
SMILES:
Clc1ccc(OCCCC(=O)NC2CCOC2=O)cc1
Structure:
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