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TargetLuciferase
LigandBDBM50352640
Substrate/Competitorn/a
Meas. Tech.ChEMBL_766351
IC50 40000±n/a nM
Citation Xiao, JMarugan, JJZheng, WTitus, SSouthall, NCherry, JJEvans, MAndrophy, EJAustin, CP Discovery, synthesis, and biological evaluation of novel SMN protein modulators. J Med Chem54:6215-33 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Luciferase
Name:Luciferase
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:60126.66
Organism:Luciola lateralis
Description:ChEMBL_786225
Residue:548
Sequence:
MENMENDENIVYGPEPFYPIEEGSAGAQLRKYMDRYAKLGAIAFTNALTGVDYTYAEYLE
KSCCLGEALKNYGLVVDGRIALCSENCEEFFIPVLAGLFIGVGVAPTNEIYTLRELVHSL
GISKPTIVFSSKKGLDKVITVQKTVTAIKTIVILDSKVDYRGYQSMDNFIKKNTPQGFKG
SSFKTVEVNRKEQVALIMNSSGSTGLPKGVQLTHENAVTRFSHARDPIYGNQVSPGTAIL
TVVPFHHGFGMFTTLGYLTCGFRIVMLTKFDEETFLKTLQDYKCSSVILVPTLFAILNRS
ELLDKYDLSNLVEIASGGAPLSKEIGEAVARRFNLPGVRQGYGLTETTSAIIITPEGDDK
PGASGKVVPLFKAKVIDLDTKKTLGPNRRGEVCVKGPMLMKGYVDNPEATREIIDEEGWL
HTGDIGYYDEEKHFFIVDRLKSLIKYKGYQVPPAELESVLLQHPNIFDAGVAGVPDPIAG
ELPGAVVVLEKGKSMTEKEVMDYVASQVSNAKRLRGGVRFVDEVPKGLTGKIDGKAIREI
LKKPVAKM
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BDBM50352640
NameBDBM50352640
Synonyms:CHEMBL1712678
TypeSmall organic molecule
Emp. Form.C16H19N3OS2
Mol. Mass.333.472
SMILESCSc1ccc(cc1)-c1cnc(s1)N1CCC(CC1)C(N)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a