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Target
Neuraminidase
Ligand
BDBM50352812
Substrate
n/a
Meas. Tech.
ChEMBL_767176 (CHEMBL1826422)
Ki
20000±n/a nM
Citation
 Park, JY; Jeong, HJ; Kim, YM; Park, SJ; Rho, MC; Park, KH; Ryu, YB; Lee, WS Characteristic of alkylated chalcones from Angelica keiskei on influenza virus neuraminidase inhibition. Bioorg Med Chem Lett 21:5602-4 (2011) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I18A0
Type:
PROTEIN
Mol. Mass.:
51401.00
Organism:
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))
Description:
ChEMBL_794312
Residue:
469
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWVSHSIQTGNQNHPETCNQSIITYENNTWVNQTYVNISNTNVVAGQDATSVILTGNSSLCPISGWAIYSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRTLMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTIMTDGPSNGQASYKILKIEKGKVTKSIELNAPNYHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPNDGTGSCGPVSSNGANGIKGFSFRYDNGVWIGRTKSTSSRSGFEMIWDPNGWTETDSSFSVRQDIVAITDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGQPKENTIWTSGSSISFCGVNSDTVGWSWPDGAELPFSIDK
  
Inhibitor
Name:
BDBM50352812
Synonyms:
CHEMBL1823414
Type:
Small organic molecule
Emp. Form.:
C26H30O5
Mol. Mass.:
422.5134
SMILES:
COc1ccc(C(=O)\C=C\c2ccc(O)cc2)c(O)c1C\C=C(/C)CCC(O)C(C)=C
Structure:
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