Reaction Details Report a problem with these data
Target
D-aspartate oxidase
Ligand
BDBM50211362
Substrate
n/a
Meas. Tech.
ChEMBL_769926 (CHEMBL1832110)
IC50
>10000±n/a nM
Citation
 Lange, JH; Venhorst, J; van Dongen, MJ; Frankena, J; Bassissi, F; de Bruin, NM; den Besten, C; de Beer, SB; Oostenbrink, C; Markova, N; Kruse, CG Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors. Eur J Med Chem 46:4808-19 (2011) [PubMed]  Article 
Target
Name:
D-aspartate oxidase
Synonyms:
DASOX | DDO | OXDD_BOVIN
Type:
PROTEIN
Mol. Mass.:
37669.70
Organism:
Bos taurus
Description:
ChEMBL_769926
Residue:
341
Sequence:
MDTVRIAVVGAGVMGLSTAVCISKMVPGCSITVISDKFTPETTSDVAAGMLIPPTYPDTPIQKQKQWFKETFDHLFAIVNSAEAEDAGVILVSGWQIFQSIPTEEVPYWADVVLGFRKMTKDELKKFPQHVFGHAFTTLKCEGPAYLPWLQKRVKGNGGLILTRRIEDLWELHPSFDIVVNCSGLGSRQLAGDSKIFPVRGQVLKVQAPWVKHFIRDSSGLTYIYPGVSNVTLGGTRQKGDWNLSPDAEISKEILSRCCALEPSLRGAYDLREKVGLRPTRPSVRLEKELLAQDSRRLPVVHHYGHGSGGIAMHWGTALEATRLVNECVQVLRTPAPKSKL
  
Inhibitor
Name:
BDBM50211362
Synonyms:
5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-3-carboxyl-pyrazole | 5-methylpyrazole-3-carboxylic acid | CHEMBL391574
Type:
Small organic molecule
Emp. Form.:
C5H6N2O2
Mol. Mass.:
126.1133
SMILES:
Cc1cc(n[nH]1)C(O)=O
Structure:
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