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Target4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
LigandBDBM50355116
Substrate/Competitorn/a
Meas. Tech.ChEMBL_772123
IC50 9000±n/a nM
Citation Tang, MOdejinmi, SIAllette, YMVankayalapati, HLai, K Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria. Bioorg Med Chem19:5886-95 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Name:4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Synonyms:4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | CMK
Type:PROTEIN
Mol. Mass.:32675.02
Organism:Yersinia pestis
Description:ChEMBL_772123
Residue:299
Sequence:
MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQ
IRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAAT
VLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVI
HPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
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  Blast E-value cutoff:
BDBM50355116
NameBDBM50355116
Synonyms:CHEMBL493923
TypeSmall organic molecule
Emp. Form.C18H14N2O2S2
Mol. Mass.354.446
SMILESOc1ccccc1C1NC(=O)C(C#N)=C(SCc2ccccc2)S1 |t:14|
Structure
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