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Target4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
LigandBDBM50355117
Substrate/Competitorn/a
Meas. Tech.ChEMBL_772123
IC50 6000±n/a nM
Citation Tang, MOdejinmi, SIAllette, YMVankayalapati, HLai, K Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria. Bioorg Med Chem19:5886-95 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Name:4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
Synonyms:4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | CMK
Type:PROTEIN
Mol. Mass.:32675.02
Organism:Yersinia pestis
Description:ChEMBL_772123
Residue:299
Sequence:
MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQ
IRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAAT
VLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVI
HPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
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  Blast E-value cutoff:
BDBM50355117
NameBDBM50355117
Synonyms:CHEMBL1835608
TypeSmall organic molecule
Emp. Form.C15H11NO3
Mol. Mass.253.2527
SMILESC=c1[nH]oc(=O)c1=Cc1ccc(o1)-c1ccccc1 |w:7.8|
Structure
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