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Target
Serine/threonine-protein kinase 32A
Ligand
BDBM50331096
Substrate
n/a
Meas. Tech.
ChEMBL_774301 (CHEMBL1908518)
Kd
>10000±n/a nM
Citation
 Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol 29:1046-51 (2011) [PubMed]  Article 
Target
Name:
Serine/threonine-protein kinase 32A
Synonyms:
ST32A_HUMAN | STK32A | YANK1
Type:
PROTEIN
Mol. Mass.:
46373.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_774301
Residue:
396
Sequence:
MGANTSRKPPVFDENEDVNFDHFEILRAIGKGSFGKVCIVQKNDTKKMYAMKYMNKQKCVERNEVRNVFKELQIMQGLEHPFLVNLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFKEETVKLFICELVMALDYLQNQRIIHRDMKPDNILLDEHGHVHITDFNIAAMLPRETQITTMAGTKPYMAPEMFSSRKGAGYSFAVDWWSLGVTAYELLRGRRPYHIRSSTSSKEIVHTFETTVVTYPSAWSQEMVSLLKKLLEPNPDQRFSQLSDVQNFPYMNDINWDAVFQKRLIPGFIPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKKEKDMRKCDSSQTCLLQEHLDSVQKEFIIFNREKVNRDFNKRQPNLALEQTKDPQGEDGQNNNL
  
Inhibitor
Name:
BDBM50331096
Synonyms:
4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline | CHEMBL491473 | Cediranib | US10464902, Cediranib | ZD-2171
Type:
Small organic molecule
Emp. Form.:
C25H27FN4O3
Mol. Mass.:
450.5053
SMILES:
COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1
Structure:
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