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Target
Calcitonin gene-related peptide 1
Ligand
BDBM50356287
Substrate
n/a
Meas. Tech.
ChEMBL_775008 (CHEMBL1912163)
IC50
2600±n/a nM
Citation
 Zartman, CB; Bell, IM; Gallicchio, SN; Graham, SL; Kane, SA; Mallee, JJ; Rutledge, RZ; Salvatore, CA; Vacca, JP; Williams, TM Identification of a novel RAMP-independent CGRP receptor antagonist. Bioorg Med Chem Lett 21:6705-8 (2011) [PubMed]  Article 
Target
Name:
Calcitonin gene-related peptide 1
Synonyms:
CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1
Type:
Enzyme
Mol. Mass.:
13902.80
Organism:
Homo sapiens (Human)
Description:
P06881
Residue:
128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
  
Inhibitor
Name:
BDBM50356287
Synonyms:
CHEMBL1910941
Type:
Small organic molecule
Emp. Form.:
C20H18F2N4O4S
Mol. Mass.:
448.443
SMILES:
Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)C(=O)NCc1cc(F)cc(F)c1
Structure:
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