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Target
G-protein coupled receptor 35
Ligand
BDBM50357198
Substrate
n/a
Meas. Tech.
ChEMBL_787830 (CHEMBL1918596)
IC50
6400±n/a nM
Citation
 Deng, H; Hu, H; He, M; Hu, J; Niu, W; Ferrie, AM; Fang, Y Discovery of 2-(4-methylfuran-2(5H)-ylidene)malononitrile and thieno[3,2-b]thiophene-2-carboxylic acid derivatives as G protein-coupled receptor 35 (GPR35) agonists. J Med Chem 54:7385-96 (2011) [PubMed]  Article 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM50357198
Synonyms:
CHEMBL1914581
Type:
Small organic molecule
Emp. Form.:
C20H19N3O
Mol. Mass.:
317.3844
SMILES:
[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)C1([#6])[#8]\[#6](=[#6](\C#N)C#N)-[#6](C#N)=[#6]1-[#6] |c:22|
Structure:
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