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Target
Scavenger receptor class B member 1
Ligand
BDBM50357536
Substrate
n/a
Meas. Tech.
ChEMBL_787603 (CHEMBL1918056)
IC50
230±n/a nM
Citation
 Mittapalli, GK; Jackson, A; Zhao, F; Lee, H; Chow, S; McKelvy, J; Wong-Staal, F; Macdonald, JE Discovery of highly potent small molecule Hepatitis C Virus entry inhibitors. Bioorg Med Chem Lett 21:6852-5 (2011) [PubMed]  Article 
Target
Name:
Scavenger receptor class B member 1
Synonyms:
CD36 and LIMPII analogous 1 | CD36 antigen-like 1 | CD36L1 | CD_antigen=CD36 | CLA-1 | CLA1 | Collagen type I receptor, thrombospondin receptor-like 1 | SCARB1 | SCRB1_HUMAN | SR-BI | SRB1
Type:
PROTEIN
Mol. Mass.:
60889.81
Organism:
Homo sapiens (Human)
Description:
ChEMBL_872680
Residue:
552
Sequence:
MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSSLSFNMWKEIPIPFYLSVYFFDVMNPSEILKGEKPQVRERGPYVYREFRHKSNITFNNNDTVSFLEYRTFQFQPSKSHGSESDYIVMPNILVLGAAVMMENKPMTLKLIMTLAFTTLGERAFMNRTVGEIMWGYKDPLVNLINKYFPGMFPFKDKFGLFAELNNSDSGLFTVFTGVQNISRIHLVDKWNGLSKVDFWHSDQCNMINGTSGQMWPPFMTPESSLEFYSPEACRSMKLMYKESGVFEGIPTYRFVAPKTLFANGSIYPPNEGFCPCLESGIQNVSTCRFSAPLFLSHPHFLNADPVLAEAVTGLHPNQEAHSLFLDIHPVTGIPMNCSVKLQLSLYMKSVAGIGQTGKIEPVVLPLLWFAESGAMEGETLHTFYTQLVLMPKVMHYAQYVLLALGCVLLLVPVICQIRSQVGAGQRAARADSHSLACWGKGASDRTLWPTAAWSPPPAAVLRLCRSGSGHCWGLRSTLASFACRVATTLPVLEGLGPSLGGGTGS
  
Inhibitor
Name:
BDBM50357536
Synonyms:
CHEMBL1914861
Type:
Small organic molecule
Emp. Form.:
C23H29N3O2
Mol. Mass.:
379.4953
SMILES:
COC(=O)c1ccc2n(CCCN3C[C@H](C)N[C@H](C)C3)c3ccccc3c2c1 |r|
Structure:
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