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TargetBcl-2-related protein A1
LigandBDBM21400
Substrate/Competitorn/a
Meas. Tech.ChEMBL_785798
Kd>1000±n/a nM
Citation Goreshnik, IBrock, AMMaly, DJ Biochemical and pharmacological profiling of the pro-survival protein Bcl-xL. Bioorg Med Chem Lett21:4951-5 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:Bcl-2-like protein 5 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:Apoptosis regulator protein
Mol. Mass.:20130.01
Organism:Homo sapiens (Human)
Description:n/a
Residue:175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVN
VVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISY
FVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM21400
NameBDBM21400
Synonyms:CHEMBL192571 | N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]-4-(4,4-dimethylpiperidin-1-yl)benzamide | Phenylpiperidine, 1a
TypeSmall organic molecule
Emp. Form.C32H41N5O5S2
Mol. Mass.639.828
SMILESCN(C)CC[C@H](CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCC(C)(C)CC1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a