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Target1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
LigandBDBM50357883
Substrate/Competitorn/a
Meas. Tech.ChEMBL_787631
Kd>5000±n/a nM
Citation Anraku, KInoue, TSugimoto, KKudo, KOkamoto, YMorii, TMori, YOtsuka, M Design and synthesis of biotinylated inositol 1,3,4,5-tetrakisphosphate targeting Grp1 pleckstrin homology domain. Bioorg Med Chem19:6833-41 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Name:1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
Synonyms:PLC-III | PLC-delta-1 | Phosphoinositide phospholipase C-delta-1 | Phospholipase C-III | Phospholipase C-delta-1
Type:PROTEIN
Mol. Mass.:85958.21
Organism:Rattus norvegicus
Description:ChEMBL_787631
Residue:756
Sequence:
MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMR
SPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQH
WVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGY
ARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQ
QREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQ
PLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTF
TSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPILLDQPLDG
VTTSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEVEAAEMEDEAVRSQVQHK
PKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFV
RHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCG
YVLKPAFLRDPNTTFNSRALTQGPWWRPERLRVRIISGQQLPKVNKNKNSIVDPKVIVEI
HGVGRDTGSRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQST
IPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50357883
NameBDBM50357883
Synonyms:CHEMBL1916342
TypeSmall organic molecule
Emp. Form.C22H42N3O17P3S
Mol. Mass.745.565
SMILESO[C@H]1[C@@H](O)[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](O)[C@H]1OP(O)(=O)OCCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a