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Target
5-hydroxytryptamine receptor 6
Ligand
BDBM50357989
Substrate
n/a
Meas. Tech.
ChEMBL_786347 (CHEMBL1920543)
Ki
1920±n/a nM
Citation
 Zajdel, P; Marciniec, K; Maslankiewicz, A; Paluchowska, MH; Satala, G; Partyka, A; Jastrzebska-Wiesek, M; Wróbel, D; Wesolowska, A; Duszynska, B; Bojarski, AJ; Pawlowski, M Arene- and quinoline-sulfonamides as novel 5-HT7 receptor ligands. Bioorg Med Chem 19:6750-9 (2011) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
46968.43
Organism:
Homo sapiens (Human)
Description:
P50406
Residue:
440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
  
Inhibitor
Name:
BDBM50357989
Synonyms:
CHEMBL1917355
Type:
Small organic molecule
Emp. Form.:
C25H32N4O3S
Mol. Mass.:
468.612
SMILES:
CCN(CCCN1CCN(CC1)c1ccccc1OC)S(=O)(=O)c1ccc2ncccc2c1
Structure:
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