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Target
Neuraminidase
Ligand
BDBM50359307
Substrate
n/a
Meas. Tech.
ChEMBL_794312 (CHEMBL1932234)
IC50
4000000±n/a nM
Citation
 Bromba, CM; Mason, JW; Brant, MG; Chan, T; Lunke, MD; Petric, M; Boulanger, MJ; Wulff, JE The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase. Bioorg Med Chem Lett 21:7137-41 (2011) [PubMed]  Article 
Target
Name:
Neuraminidase
Synonyms:
NA | NRAM_I18A0
Type:
PROTEIN
Mol. Mass.:
51401.00
Organism:
Influenza A virus (strain A/Brevig Mission/1/1918 H1N1) (Influenza Avirus (strain A/South Carolina/1/1918 H1N1))
Description:
ChEMBL_794312
Residue:
469
Sequence:
MNPNQKIITIGSICMVVGIISLILQIGNIISIWVSHSIQTGNQNHPETCNQSIITYENNTWVNQTYVNISNTNVVAGQDATSVILTGNSSLCPISGWAIYSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRTLMSCPVGEAPSPYNSRFESVAWSASACHDGMGWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTIMTDGPSNGQASYKILKIEKGKVTKSIELNAPNYHYEECSCYPDTGKVMCVCRDNWHGSNRPWVSFDQNLDYQIGYICSGVFGDNPRPNDGTGSCGPVSSNGANGIKGFSFRYDNGVWIGRTKSTSSRSGFEMIWDPNGWTETDSSFSVRQDIVAITDWSGYSGSFVQHPELTGLDCMRPCFWVELIRGQPKENTIWTSGSSISFCGVNSDTVGWSWPDGAELPFSIDK
  
Inhibitor
Name:
BDBM50359307
Synonyms:
CHEMBL1928609
Type:
Small organic molecule
Emp. Form.:
C7H13N3O3
Mol. Mass.:
187.1964
SMILES:
[#7]\[#6](-[#7])=[#7]\[#6@H]-1-[#6]-[#6][C@]([#8])([#6]1)[#6](-[#8])=O |r|
Structure:
Search PDB for entries with ligand similarity: