Reaction Details Report a problem with these data
Target
Macrophage migration inhibitory factor
Ligand
BDBM50359714
Substrate
n/a
Meas. Tech.
ChEMBL_791791 (CHEMBL1931369)
IC50
7300±n/a nM
Citation
 Alam, A; Pal, C; Goyal, M; Kundu, MK; Kumar, R; Iqbal, MS; Dey, S; Bindu, S; Sarkar, S; Pal, U; Maiti, NC; Adhikari, S; Bandyopadhyay, U Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent. Bioorg Med Chem 19:7365-73 (2011) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50359714
Synonyms:
CHEMBL1927069
Type:
Small organic molecule
Emp. Form.:
C18H17NO5
Mol. Mass.:
327.3313
SMILES:
COc1cc(ccc1O)C1=NOC(COc2ccc(C=O)cc2)C1 |t:10|
Structure:
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