Reaction Details Report a problem with these data
Target
Alpha-1A adrenergic receptor
Ligand
BDBM50359758
Substrate
n/a
Meas. Tech.
ChEMBL_791620 (CHEMBL1930844)
Ki
1800±n/a nM
Citation
 Huber, D; Löber, S; Hübner, H; Gmeiner, P Bivalent molecular probes for dopamine D2-like receptors. Bioorg Med Chem 20:455-66 (2011) [PubMed]  Article 
Target
Name:
Alpha-1A adrenergic receptor
Synonyms:
Uncharacterized protein
Type:
PROTEIN
Mol. Mass.:
51698.80
Organism:
Sus scrofa
Description:
ChEMBL_791620
Residue:
466
Sequence:
MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLIIFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSRHALGYTLHPTSHALEEQHKDLVRIPVGSGETFYKISKTDGVCEWKFFSSMPRASARITVPKDPSACTTARVRSKNFLQVCCCMGPSTPSRDENHPIPTIKIHTISLSENGEEV
  
Inhibitor
Name:
BDBM50359758
Synonyms:
CHEMBL1928247
Type:
Small organic molecule
Emp. Form.:
C27H39N3O4
Mol. Mass.:
469.6163
SMILES:
CCOCCOCc1ccc(N2CCN(CCCCNC(=O)c3ccccc3)CC2)c(OC)c1
Structure:
Search PDB for entries with ligand similarity: