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Target
Prostaglandin E2 receptor EP2 subtype
Ligand
BDBM50360153
Substrate
n/a
Meas. Tech.
ChEMBL_793558 (CHEMBL1932309)
Ki
1100±n/a nM
Citation
 Kambe, T; Maruyama, T; Nagase, T; Ogawa, S; Minamoto, C; Sakata, K; Maruyama, T; Nakai, H; Toda, M Synthesis and evaluation of novel modified¿-lactam prostanoids as EP4 subtype-selective agonists. Bioorg Med Chem 20:702-13 (2012) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP2 subtype
Synonyms:
PE2R2_MOUSE | PGE receptor, EP2 subtype | Prostaglandin E2 | Prostaglandin E2 receptor EP2 subtype | Prostanoid EP2 receptor | Ptger2 | Ptgerep2
Type:
G-protein coupled receptor
Mol. Mass.:
40495.26
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
362
Sequence:
MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL
  
Inhibitor
Name:
BDBM50360153
Synonyms:
CHEMBL1929546
Type:
Small organic molecule
Emp. Form.:
C23H33NO3S
Mol. Mass.:
403.578
SMILES:
CCc1cccc(C[C@H](O)\C=C\[C@H]2CCC(=S)N2CCCCCCC(O)=O)c1 |r|
Structure:
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