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Target
ATP-dependent Clp protease proteolytic subunit
Ligand
BDBM50360280
Substrate
n/a
Meas. Tech.
ChEMBL_796596 (CHEMBL1937911)
EC50
4500±n/a nM
Citation
 Zeiler, E; Korotkov, VS; Lorenz-Baath, K; Böttcher, T; Sieber, SA Development and characterization of improvedß-lactone-based anti-virulence drugs targeting ClpP. Bioorg Med Chem 20:583-91 (2012) [PubMed]  Article 
Target
Name:
ATP-dependent Clp protease proteolytic subunit
Synonyms:
CLPP_STAA8 | Endopeptidase Clp | clpP
Type:
PROTEIN
Mol. Mass.:
21508.79
Organism:
Staphylococcus aureus (strain NCTC 8325)
Description:
ChEMBL_796596
Residue:
195
Sequence:
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
  
Inhibitor
Name:
BDBM50360280
Synonyms:
CHEMBL1933114
Type:
Small organic molecule
Emp. Form.:
C19H27NO2
Mol. Mass.:
301.4232
SMILES:
C=CCCCCCCC[C@@H]1[C@@H](CCc2cccnc2)OC1=O |r|
Structure:
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