Reaction Details Report a problem with these data
Target
B1 bradykinin receptor
Ligand
BDBM50355069
Substrate
n/a
Meas. Tech.
ChEMBL_796432 (CHEMBL1937747)
IC50
476±n/a nM
Citation
 Bryan, MC; Biswas, K; Peterkin, TA; Rzasa, RM; Arik, L; Lehto, SG; Sun, H; Hsieh, FY; Xu, C; Fremeau, RT; Allen, JR Chromenones as potent bradykinin B1 antagonists. Bioorg Med Chem Lett 22:619-22 (2011) [PubMed]  Article 
Target
Name:
B1 bradykinin receptor
Synonyms:
BDKRB1 | BKRB1_RABIT | Bradykinin B1 receptor
Type:
PROTEIN
Mol. Mass.:
39519.62
Organism:
Oryctolagus cuniculus
Description:
ChEMBL_796432
Residue:
352
Sequence:
MASQGPLELQPSNQSQLAPPNATSCSGAPDAWDLLHRLLPTFIIAIFTLGLLGNSFVLSVFLLARRRLSVAEIYLANLAASDLVFVLGLPFWAENVRNQFDWPFGAALCRIVNGVIKANLFISIFLVVAISQDRYSVLVHPMASRRGRRRRQAQATCALIWLAGGLLSTPTFVLRSVRAVPELNVSACILLLPHEAWHWLRMVELNLLGFLLPLAAILFFNCHILASLRRRGERVPSRCGGPRDSKSTALILTLVASFLVCWAPYHFFAFLECLWQVHAIGGCFWEEFTDLGLQLSNFSAFVNSCLNPVIYVFVGRLFRTKVWELCQQCSPRSLAPVSSSRRKEMLWGFWRN
  
Inhibitor
Name:
BDBM50355069
Synonyms:
CHEMBL1835756
Type:
Small organic molecule
Emp. Form.:
C32H32N2O3
Mol. Mass.:
492.6081
SMILES:
O=C(N[C@@H]1CCCc2cc(CN3CCCCC3)ccc12)c1cccc(c1)-c1coc2ccccc2c1=O |r|
Structure:
Search PDB for entries with ligand similarity: