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Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50360740
Substrate
n/a
Meas. Tech.
ChEMBL_796446 (CHEMBL1937761)
EC50
2700±n/a nM
Citation
 Nomura, M; Yumoto, K; Shinozaki, T; Isogai, S; Takano, Y; Murakami, K Discovery of cyclic amine-substituted benzoic acids as PPARa agonists. Bioorg Med Chem Lett 22:334-8 (2011) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | Nuclear receptor subfamily 1 group C member 2 | PPAR-beta | PPAR-delta | PPARB | PPARD | PPARD_CANLF | Peroxisome proliferator-activated receptor beta
Type:
PROTEIN
Mol. Mass.:
49786.42
Organism:
Canis familiaris
Description:
ChEMBL_796446
Residue:
441
Sequence:
MEQPPGEAAEVREEEEKKEVAEAEGAPELNGGPERSLPSSSYTDLSRSSSPPSLLDQLQMGGDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERICKIQKKNRNKCQYCRFQKCVALGMSHNAIRFGRMPEAEKRKLVAGLTANEGTQHNPQVADLKAFSKHIYNAYLKNFNMTKKKARGILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSNLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGTGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLINVPQVEAIQDTILRALEFHLQANHPYAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50360740
Synonyms:
CHEMBL1934476
Type:
Small organic molecule
Emp. Form.:
C23H22ClN3O3S
Mol. Mass.:
455.957
SMILES:
Cc1nc(sc1C(=O)N[C@H]1CCCN(C1)c1cccc(c1)C(O)=O)-c1ccc(Cl)cc1 |r|
Structure:
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