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Target
Histone deacetylase-like amidohydrolase
Ligand
BDBM50361266
Substrate
n/a
Meas. Tech.
ChEMBL_795335 (CHEMBL1937191)
Kd
290±n/a nM
Citation
 Henkes, LM; Haus, P; Jäger, F; Ludwig, J; Meyer-Almes, FJ Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-octanediamides as inhibitors of human histone deacetylases. Bioorg Med Chem 20:985-95 (2012) [PubMed]  Article 
Target
Name:
Histone deacetylase-like amidohydrolase
Synonyms:
HDAH_ALCSD | hdaH | hdaH1
Type:
PROTEIN
Mol. Mass.:
39419.78
Organism:
Alcaligenes sp. (strain DSM 11172) (Bordetella sp. (strain FB188))
Description:
ChEMBL_827139
Residue:
369
Sequence:
MAIGYVWNTLYGWVDTGTGSLAAANLTARMQPISHHLAHPDTKRRFHELVCASGQIEHLTPIAAVAATDADILRAHSAAHLENMKRVSNLPTGGDTGDGITMMGNGGLEIARLSAGGAVELTRRVATGELSAGYALVNPPGHHAPHNAAMGFCIFNNTSVAAGYARAVLGMERVAILDWDVHHGNGTQDIWWNDPSVLTISLHQHLCFPPDSGYSTERGAGNGHGYNINVPLPPGSGNAAYLHAMDQVVLHALRAYRPQLIIVGSGFDASMLDPLARMMVTADGFRQMARRTIDCAADICDGRIVFVQEGGYSPHYLPFCGLAVIEELTGVRSLPDPYHEFLAGMGGNTLLDAERAAIEEIVPLLADIR
  
Inhibitor
Name:
BDBM50361266
Synonyms:
CHEMBL1934908
Type:
Small organic molecule
Emp. Form.:
C22H12F12N2O3
Mol. Mass.:
580.3231
SMILES:
ONC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1cc2ccccc2c2ccccc12
Structure:
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