Reaction Details Report a problem with these data
Target
Glutathione S-transferase A2
Ligand
BDBM50361800
Substrate
n/a
Meas. Tech.
ChEMBL_799590 (CHEMBL1941296)
IC50
37800±n/a nM
Citation
 Wang, CH; Wu, HT; Cheng, HM; Yen, TJ; Lu, IH; Chang, HC; Jao, SC; Shing, TK; Li, WS Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells. J Med Chem 54:8574-81 (2011) [PubMed]  Article 
Target
Name:
Glutathione S-transferase A2
Synonyms:
GST class-alpha member 2 | GST-gamma | GST2 | GSTA2 | GSTA2-2 | GSTA2_HUMAN | GTH2 | HA subunit 2
Type:
PROTEIN
Mol. Mass.:
25667.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_799590
Residue:
222
Sequence:
MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYLMFQQVPMVEIDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDAKLALIQEKTKNRYFPAFEKVLKSHGQDYLVGNKLSRADIHLVELLYYVEELDSSLISSFPLLKALKTRISNLPTVKKFLQPGSPRKPPMDEKSLEESRKIFRF
  
Inhibitor
Name:
BDBM50361800
Synonyms:
CHEMBL1938641
Type:
Small organic molecule
Emp. Form.:
C19H32O6
Mol. Mass.:
356.4538
SMILES:
CCCCCCCCCCO[C@H]1CC(COC(C)=O)C(=O)C(=O)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: