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Target
Met repressor
Ligand
BDBM50362005
Substrate
n/a
Meas. Tech.
ChEMBL_799628 (CHEMBL1941334)
EC50
111±n/a nM
Citation
 Joce, C; White, R; Stockley, PG; Warriner, S; Turnbull, WB; Nelson, A Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues. Bioorg Med Chem Lett 22:278-84 (2011) [PubMed]  Article 
Target
Name:
Met repressor
Synonyms:
Met regulon regulatory protein MetJ
Type:
PROTEIN
Mol. Mass.:
12138.09
Organism:
Escherichia coli
Description:
ChEMBL_799627
Residue:
105
Sequence:
MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPETWEY
  
Inhibitor
Name:
BDBM50362005
Synonyms:
CHEMBL1939708
Type:
Small organic molecule
Emp. Form.:
C36H50N16O8
Mol. Mass.:
834.8846
SMILES:
CN(CC[C@H](N)C(=O)NCC#CC#CCNC(=O)[C@@H](N)CCN(C)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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