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Target
D(4) dopamine receptor
Ligand
BDBM50362853
Substrate
n/a
Meas. Tech.
ChEMBL_797753 (CHEMBL1944112)
Ki
7.8±n/a nM
Citation
 Peprah, K; Zhu, XY; Eyunni, SV; Setola, V; Roth, BL; Ablordeppey, SY Multi-receptor drug design: Haloperidol as a scaffold for the design and synthesis of atypical antipsychotic agents. Bioorg Med Chem 20:1291-7 (2012) [PubMed]  Article 
Target
Name:
D(4) dopamine receptor
Synonyms:
D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41307.65
Organism:
RAT
Description:
DOPAMINE D4.4 0 RAT::P30729
Residue:
387
Sequence:
MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
  
Inhibitor
Name:
BDBM50362853
Synonyms:
CHEMBL1940408
Type:
Small organic molecule
Emp. Form.:
C20H24ClFN2
Mol. Mass.:
346.869
SMILES:
Fc1ccc(CCCCN2CCN(CC2)c2ccc(Cl)cc2)cc1
Structure:
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