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Target
Carbonic anhydrase
Ligand
BDBM10870
Substrate
n/a
Meas. Tech.
ChEMBL_801827 (CHEMBL1947439)
Ki
3.9±n/a nM
Citation
 Ohradanova, A; Vullo, D; Pastorekova, S; Pastorek, J; Jackson, DJ; Wörheide, G; Supuran, CT Cloning, characterization and sulfonamide inhibition studies of ana-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. Bioorg Med Chem 20:1403-10 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
Astrosclerin-3
Type:
PROTEIN
Mol. Mass.:
33233.07
Organism:
Astrosclera willeyana
Description:
ChEMBL_801827
Residue:
292
Sequence:
MMAYKVLHFVVISLGLVTLVASRCDFNYYNQRAWLSCPGSQCGGNRQSPINIDTEKTKANNSLIALRFNDYDDPVDGDFENLGTTVEFVPETKDATLTNHLGTYDLLQFHFHWGRDSSEGSEHRIDDEQYSAEIHFVHLKQGASPSDTAGDTFSVVAVLCEAADIPIRGVWAKLSPVPTGHEDSHSVSDLVYTDLLPRNRDYYHYEGSLTTPLCDETVQWFVLKNTIKIPKAFLTMLRRVESDEDGTLLTFNFRNLQRLNGRQVFEFPPDVDNGEDKKRKRRNNRHGRDHHG
  
Inhibitor
Name:
BDBM10870
Synonyms:
2-N-(4-aminobenzene)-1,3,4-thiadiazole-2,5-disulfonamide | Aminobenzolamide 12 | CHEMBL268439 | aminobenzolamide 17a | aminobenzolamide deriv. 43 | aromatic/heteroaromatic sulfonamide 15
Type:
Small organic molecule
Emp. Form.:
C8H9N5O4S3
Mol. Mass.:
335.383
SMILES:
Nc1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O
Structure:
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