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Target
Cannabinoid receptor 1
Ligand
BDBM50364078
Substrate
n/a
Meas. Tech.
ChEMBL_803201 (CHEMBL1954912)
EC50
321±n/a nM
Citation
 Gijsen, HJ; De Cleyn, MA; Surkyn, M; Van Lommen, GR; Verbist, BM; Nijsen, MJ; Meert, T; Wauwe, JV; Aerssens, J 5-sulfonyl-benzimidazoles as selective CB2 agonists-part 2. Bioorg Med Chem Lett 22:547-52 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50364078
Synonyms:
CHEMBL1950933
Type:
Small organic molecule
Emp. Form.:
C21H26N4O3S2
Mol. Mass.:
446.586
SMILES:
CC(C)(C)c1nc2cc(ccc2n1CC1CCN(CC1)C=O)S(=O)(=O)c1nccs1
Structure:
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