Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50364097
Substrate
n/a
Meas. Tech.
ChEMBL_803200 (CHEMBL1954911)
EC50
8.4±n/a nM
Citation
 Gijsen, HJ; De Cleyn, MA; Surkyn, M; Van Lommen, GR; Verbist, BM; Nijsen, MJ; Meert, T; Wauwe, JV; Aerssens, J 5-sulfonyl-benzimidazoles as selective CB2 agonists-part 2. Bioorg Med Chem Lett 22:547-52 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50364097
Synonyms:
CHEMBL1950923
Type:
Small organic molecule
Emp. Form.:
C21H31N3O3S
Mol. Mass.:
405.554
SMILES:
CCS(=O)(=O)c1ccc2n(CC3CCN(CC3)C(C)=O)c(nc2c1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: