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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50364456
Substrate
n/a
Meas. Tech.
ChEMBL_802417 (CHEMBL1954860)
Ki
1630±n/a nM
Citation
 Song, B; Xiao, T; Qi, X; Li, LN; Qin, K; Nian, S; Hu, GX; Yu, Y; Liang, G; Ye, F Design and synthesis of 8-substituted benzamido-phenylxanthine derivatives as MAO-B inhibitors. Bioorg Med Chem Lett 22:1739-42 (2012) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_MOUSE | Amine oxidase [flavin-containing] B | MAO-B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase type B
Type:
PROTEIN
Mol. Mass.:
58568.67
Organism:
Mus musculus
Description:
ChEMBL_605809
Residue:
520
Sequence:
MSNKSDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDNNNLWRTMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTKSTKQIATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQTGENVIVKTLNHEIYEAKYVISAIPPALGMKIHYSPPLPMLRNQLISRVPLGSVIKCMVYYKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGTYAAIMGFILAHKARKLVRLTKEERLRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVGKIFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESLDVPARPITSTFLERHLPSVPGLLKLFGLTTILSATALGFLAHKRGLFVHF
  
Inhibitor
Name:
BDBM50364456
Synonyms:
CHEMBL1950683
Type:
Small organic molecule
Emp. Form.:
C22H21N5O3
Mol. Mass.:
403.4338
SMILES:
Cc1ccc(cc1)C(=O)Nc1ccc(cc1)-c1nc2n(C)c(=O)n(C)c(=O)c2n1C
Structure:
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