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Target
Mu-type opioid receptor
Ligand
BDBM50365853
Substrate
n/a
Meas. Tech.
ChEMBL_806704 (CHEMBL1958664)
Ki
0.3±n/a nM
Citation
 Lunn, G; Roberts, LR; Content, S; Critcher, DJ; Douglas, S; Fenwick, AE; Gethin, DM; Goodwin, G; Greenway, D; Greenwood, S; Hall, K; Thomas, M; Thompson, S; Williams, D; Wood, G; Wylie, A SAR and biological evaluation of 3-azabicyclo[3.1.0]hexane derivatives asµ opioid ligands. Bioorg Med Chem Lett 22:2200-3 (2012) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50365853
Synonyms:
CHEMBL1957717
Type:
Small organic molecule
Emp. Form.:
C23H28N2O2S
Mol. Mass.:
396.546
SMILES:
C[C@]1([C@H]2CN(CC3Cc4ccccc4C3)C[C@@H]12)c1cccc(NS(C)(=O)=O)c1 |r|
Structure:
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