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Target
Chymotrypsinogen A
Ligand
BDBM50366092
Substrate
n/a
Meas. Tech.
ChEMBL_808108 (CHEMBL1961259)
IC50
>10000±n/a nM
Citation
 Iqbal, M; Messina McLaughlin, PA; Dunn, D; Mallya, S; Husten, J; Ator, MA; Chatterjee, S Proteasome inhibitors for cancer therapy. Bioorg Med Chem 20:2362-8 (2012) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50366092
Synonyms:
CHEMBL1957052
Type:
Small organic molecule
Emp. Form.:
C27H50BN7O6
Mol. Mass.:
579.54
SMILES:
CC(C)C[C@H](NC(=O)[C@H](CCCN=C(N)N[N+]([O-])=O)NC(=O)C(CCCCCCCCC#N)C1CCCC1)B(O)O |r,w:12.11|
Structure:
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