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Reaction Details
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TargetNeurotensin receptor 1
LigandBDBM50281811
Substrate/Competitorn/a
Meas. Tech.ChEBML_144304
Ki 120±n/a nM
Citation Cain, GAChristos, TEJohnson, ALPottorf, RSConfalone, PNWilliam Tam, SSchmidt, WK Neurotensin receptor binding and antinociceptive activity for lipophilic N-amido neurotensin(913) analogs Bioorg Med Chem Lett3:2055-2060 (1993)    Article
More Info.:Get all data from this article,  Assay Method
 
Neurotensin receptor 1
Name:Neurotensin receptor 1
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:47070.64
Organism:Rattus norvegicus
Description:ChEMBL_1466612
Residue:424
Sequence:
MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTD
IYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLA
MPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTL
MSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQV
NTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRV
QALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYV
SSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATR
ETLY
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50281811
NameBDBM50281811
Synonyms:(S)-2-{(2S,3S)-2-[(S)-2-[((S)-1-{(S)-2-[(Adamantane-1-carbonyl)-amino]-6-amino-hexanoyl}-pyrrolidine-2-carbonyl)-amino]-3-(4-hydroxy-phenyl)-propionylamino]-3-methyl-pentanoylamino}-4-methyl-pentanoic acid | CHEMBL2372106
TypeSmall organic molecule
Emp. Form.C43H66N6O8
Mol. Mass.795.0195
SMILESCC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)N[C@@H](CC(C)C)C(O)=O |TLB:39:40:44:37.38.43,THB:41:40:37:44.42.43,41:42:37:45.40.39,39:38:44:45.40.41|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a