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Target
Neurotensin receptor type 1
Ligand
BDBM50366312
Substrate
n/a
Meas. Tech.
ChEBML_144304
Ki
>10000±n/a nM
Citation
 Cain, GA; Christos, TE; Johnson, AL; Pottorf, RS; Confalone, PN; William Tam, S; Schmidt, WK Neurotensin receptor binding and antinociceptive activity for lipophilic N-amido neurotensin(913) analogs Bioorg Med Chem Lett 3:2055-2060 (1993)    Article 
Target
Name:
Neurotensin receptor type 1
Synonyms:
NTR1_RAT | Neurotensin receptor 1 | Ntsr | Ntsr1
Type:
PROTEIN
Mol. Mass.:
47070.64
Organism:
Rattus norvegicus
Description:
ChEMBL_1466612
Residue:
424
Sequence:
MHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
  
Inhibitor
Name:
BDBM50366312
Synonyms:
CHEMBL1790476
Type:
Small organic molecule
Emp. Form.:
C50H86N6O8
Mol. Mass.:
899.2532
SMILES:
CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](CC(C)C)C(O)=O
Structure:
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