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Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50029816
Substrate
n/a
Meas. Tech.
ChEMBL_122946 (CHEMBL733231)
IC50
>10000±n/a nM
Citation
 Rendenbach-Muller, B; Schlecker, R; Traut, M; Weifenbach, H Synthesis of coumarins as subtype-selective inhibitors of monoamine oxidase Bioorg Med Chem Lett 4:1195-1198 (1994)    Article 
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA)
Type:
Enzyme
Mol. Mass.:
59515.21
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
526
Sequence:
MTDLEKPNLAGHMFDVGLIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEMGKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNIIVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRQAKLHKDIRKRKICELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERNLPSVPGLLKITGVSTSVALLCFVLYKIKKLPC
  
Inhibitor
Name:
BDBM50029816
Synonyms:
5-Chloro-pyridine-2-carboxylic acid (2-amino-ethyl)-amide | CHEMBL279390 | Lazabemide | Ro-19-6327
Type:
Small organic molecule
Emp. Form.:
C8H10ClN3O
Mol. Mass.:
199.638
SMILES:
NCCNC(=O)c1ccc(Cl)cn1
Structure:
Search PDB for entries with ligand similarity: