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Target
3-phosphoshikimate 1-carboxyvinyltransferase
Ligand
BDBM50283585
Substrate
n/a
Meas. Tech.
ChEMBL_64948 (CHEMBL675693)
IC50
10000000±n/a nM
Citation
 Miller, MJ; Braccolino, DS; Clearly, DG; Ream, JE; Walker, MC; Sikorski, JA EPSP synthase inhibitor design IV. New aromatic substrate analogs and symmetrical inhibitors containing novel 3-phosphate mimics. Bioorg Med Chem Lett 4:2605-2608 (1994)    Article 
Target
Name:
3-phosphoshikimate 1-carboxyvinyltransferase
Synonyms:
5-enolpyruvylshikimate-3-phosphate synthase | AROA_ECOLI | aroA
Type:
PROTEIN
Mol. Mass.:
46089.22
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_65087
Residue:
427
Sequence:
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA
  
Inhibitor
Name:
BDBM50283585
Synonyms:
CHEMBL89228 | Sodium; 3-dicarboxymethoxy-5-hydroxy-benzoate
Type:
Small organic molecule
Emp. Form.:
C10H7O8
Mol. Mass.:
255.1583
SMILES:
OC(=O)C(Oc1cc(O)cc(c1)C([O-])=O)C(O)=O
Structure:
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